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Creators/Authors contains: "Xu, Jianbin"

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  1. Free, publicly-accessible full text available December 1, 2025
  2. Abstract A Rh(I)‐catalyzed C6‐selective C−H arylation of 2‐pyridones with inexpensive, readily available, safe and structurally diverse aryl carboxylic acids with the aid of a pyridine directing group is developed. This decarbonylative arylation protocol features an easy‐to‐handle catalytic system, and is amenable to diversely substituted 2‐pyridones and aryl carboxylic acids. It allows access to a wide range of C6‐arylated 2‐pyridones, including those that are difficult to prepare using conventional C−H arylation processes. The method tolerates various electron‐neutral, electron‐rich and electron‐deficient functional groups, and affords the products in 41–91% yields. magnified image 
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